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- PerMM
The PerMM web server is a computational tool for theoretical assessment of passive permeability of molecules across the lipid bilayer The underlying thermodynamics-based method is based on inhomogeneous solubility-diffusion theory and operates with atomic 3D structures of solutes and the anisotropic solvent model of the DOPC bilayer characterized by transbilayer profiles of dielectric and
- CellPM - permm. phar. umich. edu
The discovery of a new class of cell-penetrating peptides (CPPs) two decade ago rapidly changed the general view on the inability of highly polar and charged molecules to enter cells without causing irreversible membrane damage Here we provide CELLPM, a web-based tool aimed at validation of ability of peptides to passively penetrate across the lipid bilayer This tool implements novel
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